Type-Specific Antigens of Group B Type Ic Streptococci

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Type-specific Polysaccharide Antigens of Group B Streptococci

The type-specific antigen of Group B Type II streptococci has been prepared free of other known cell components. This antigen is a capsular polysaccharide containing D-galactose, D-glucose, N-acetyl-D-glucosamine, and a labile component which has not been chemically characterized. Extraction of Type II streptococci with cold TCA yielded this antigen which contained two serological determinants....

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Serological relationships of type I antigens of group B streptococci.

Some of the complex antigenic relationships of type I group B streptococci from various clinical sources were defined by means of immunodiffusion, absorption, and precipitin tests. Three predominant types are described: Ia, Ib, and Ii. Methods for preparing antisera for differentiating type I strains are presented.

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Isolation of type-specific polysaccharide antigen from group B type Ib streptococci

Group B streptococcus type Ib (strain H36B) was subjected to digestion with extracellular muralytic enzymes prepared from Streptomyces albus. Type Ib-specific polysaccharide antigen was isolated from the lysate by alcohol precipitation and Sepharose 6B chromatography. The purified type Ib antigen has a Kd value of 0.31 on a Sepharose 4B column and contains four sugars, galactose, glucose, N-ace...

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Immunochemistry of purified polysaccharide type antigens of group B streptococcal types Ia, Ib, and Ic.

The HCl-extracted purified polysaccharide type antigens of group B Streptococcus types Ia and Ib were composed of galactose and N-acetylglucosamine in a molar ratio of 3:1 for the Ia antigen and 2:1 for the Ib antigen. Immunochemical data were the same for the Ia antigens of type Ia, purified in this study, and type Ic, purified earlier. Glucosamine inhibited the Ib quantitative precipitin reac...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1971

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.4.5.596-604.1971